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医学翻译之免疫组化相关翻译内容

发布日期:2019-09-21 10:56:03   浏览量:743
免疫组化,是应用免疫学基本原理——抗原抗体反应,即抗原与抗体特异性结合的原理,通过化学反应使标记抗体的显色剂(荧光素、酶、金属离子、同位素)显色来确定组织细胞内抗原(多肽和蛋白质),对其进行定位、定性及相对定量的研究,称为免疫组织化学技术(immunohistochemistry)或免疫细胞化学技术(immunocytochemistry)。

免疫组织化学的临床应用主要包括以下几方面:
⑴恶性肿瘤的诊断与鉴别诊断;
⑵确定转移性恶性肿瘤的原发部位;
⑶对某类肿瘤进行进一步的病理分型;
⑷软组织肿瘤的治疗一般需根据正确的组织学分类,因其种类多、组织形态相像,有时难以区分其组织来源,应用多种标志进行免疫组化研究对软组织肿瘤的诊断是不可缺少的;
⑸发现微小转移灶,有助于临床治疗方案的确定,包括手术范围的确定。
⑹为临床提供治疗方案的选择。

The clinical application of immunohistochemistry mainly includes the following aspects:
(1) Diagnosis and differential diagnosis of malignant tumors;
(2) determining the primary site of the metastatic malignant tumor;
(3) further pathological typing of certain types of tumors;
(4) The treatment of soft tissue tumors generally needs to be classified according to the correct histology. Because of its variety and tissue morphology, it is sometimes difficult to distinguish its tissue source. The application of multiple markers for immunohistochemical research is indispensable for the diagnosis of soft tissue tumors;
(5) The discovery of micrometastases helps to determine the clinical treatment plan, including the determination of the scope of surgery.
(6) Provide a choice of treatment options for the clinic.

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